Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097325 | 1.00 | SLC22A1 (0.51) | SLC22A1SLC6A4SLC6A2OPRM1OPRD1 | |
| SCHEMBL10987950 | 0.87 | SLC22A1 (0.54) | SLC22A1SLC6A4SLC6A2OPRM1OPRD1 | |
| SCHEMBL8105104 | 0.86 | SLC22A1 (0.53) | SLC22A1SLC6A4SLC6A2OPRM1OPRD1 | |
| SCHEMBL10830448 | 0.84 | SLC22A1 (0.52) | SLC22A1SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL9993716 | 0.84 | SLC6A2 (0.63) | SLC6A4SLC6A2HTR2C | |
| SCHEMBL15433975 | 0.84 | SLC6A2 (0.63) | SLC6A4SLC6A2HTR2C | |
| SCHEMBL3087335 | 0.84 | SLC6A2 (0.63) | SLC6A4SLC6A2HTR2C | |
| SCHEMBL13720895 | 0.84 | SLC22A1 (0.52) | SLC22A1SLC6A4SLC6A2OPRM1OPRD1 | |
| SCHEMBL8110533 | 0.84 | SLC6A2 (0.48) | SLC6A4SLC6A2HTR2CSIGMAR1 | |
| SCHEMBL8105017 | 0.84 | SLC6A2 (0.48) | SLC6A4SLC6A2HTR2CSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124354-A | TREATMENT OF URINARY INCONTINENCE OR IRRITABLE BOWEL SYNDROME | PHARMACIA & UPJOHN AB (SE) | 2000-09-26 | — | — | US | disclosed |
| EP-0923536-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004517-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-02-05 | — | — | WO | disclosed |