Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.58 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21457762 | 0.91 | ALDH1A1 (0.69) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL21457759 | 0.91 | ALDH1A1 (0.69) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL8102210 | 0.90 | KDM4E (0.52) | ALDH1A1MAPTKDM4EGAANPSR1 | |
| SCHEMBL11138248 | 0.88 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL11138247 | 0.88 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL2139676 | 0.87 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL2139678 | 0.87 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL4317761 | 0.87 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL20357998 | 0.87 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 | |
| SCHEMBL10703771 | 0.87 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4EL3MBTL1PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991708-A1 | POLYESTER CONTAINING BENZYLIDENE HAVING REDUCED FLUORESCENCE | EASTMAN CHEMICAL COMPANY (US) | 2000-04-12 | — | — | EP | disclosed |
| US-6001952-A | Polyester containing benzylidene having reduced fluorescence | EASTMAN CHEMICAL COMPANY (US) | 1999-12-14 | — | — | US | disclosed |
| WO-1998058016-A1 | POLYESTER CONTAINING BENZYLIDENE HAVING REDUCED FLUORESCENCE | EASTMAN CHEMICAL COMPANY (US) | 1998-12-23 | — | — | WO | disclosed |