Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 19/20 | 0.86 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.75 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663767 | 0.93 | ADORA3 (1.00) | ADORA3ADORA2BADORA2AADORA1ALDH1A1 | |
| SCHEMBL1666099 | 0.86 | ADORA3 (1.00) | ADORA3ADORA2BADORA2AADORA1ALDH1A1 | |
| SCHEMBL1663612 | 0.83 | ADORA3 (1.00) | ADORA3ADORA2BADORA2AADORA1ALDH1A1 | |
| SCHEMBL8106742 | 0.83 | ADORA3 (1.00) | ADORA3ADORA2BADORA2AADORA1ALDH1A1 | |
| SCHEMBL8111292 | 0.83 | ADORA3 (1.00) | ADORA3ADORA2BADORA2AADORA1ALDH1A1 | |
| SCHEMBL6379174 | 0.82 | ADORA3 (0.91) | ADORA3ADORA2BADORA2AADORA1ALDH1A1 | |
| SCHEMBL29386608 | 0.82 | ADORA3 (1.00) | ADORA3ADORA2BADORA2AADORA1ALDH1A1 | |
| SCHEMBL927261 | 0.82 | ADORA3 (1.00) | ADORA3ADORA2BADORA2AADORA1ALDH1A1 | |
| SCHEMBL1663534 | 0.81 | ADORA3 (1.00) | ADORA3ADORA2B | |
| SCHEMBL10713122 | 0.80 | ADORA3 (0.76) | ADORA3ADORA2BADORA2AADORA1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066642-A | FOR SELECTIVELY BLOCKING THE A3 ADENOSINE RECEPTOR OF A MAMMAL | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-05-23 | — | — | US | disclosed |