Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090605 | 0.87 | GUSB (0.42) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL8098504 | 0.85 | KMT2A (0.45) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL8090125 | 0.83 | GUSB (0.44) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL8090428 | 0.82 | MAPT (0.40) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL8090064 | 0.82 | GUSB (0.43) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL8098712 | 0.81 | NPSR1 (0.46) | LMNAALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL8106106 | 0.79 | EPHX2 (0.47) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL8099407 | 0.78 | GUSB (0.45) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL8792372 | 0.78 | ALDH1A1 (0.41) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL8106100 | 0.74 | NPSR1 (0.43) | LMNAALDH1A1MAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |