Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8360658 | 0.74 | GRIA1 (0.39) | POLB | |
| SCHEMBL19103690 | 0.70 | — | — | |
| SCHEMBL19115401 | 0.67 | — | — | |
| SCHEMBL3411817 | 0.67 | — | — | |
| SCHEMBL24815825 | 0.65 | POLB (0.30) | POLB | |
| SCHEMBL7657039 | 0.64 | GRIA4 (0.34) | — | |
| SCHEMBL24815857 | 0.64 | — | — | |
| SCHEMBL9391988 | 0.62 | — | — | |
| SCHEMBL1726899 | 0.62 | — | — | |
| SCHEMBL26144753 | 0.62 | GRIA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147115-A | SULFONYLUREIDO-4-HALOBENZENE DERIVATIVES; ANTICARCINOGENIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-11-14 | — | — | US | disclosed |
| EP-0467621-B1 | N-phenyl-N'-alkylsulfonylureas, process for their preparation and antitumor compositions containing them | LILLY CO ELI (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5216026-A | Administering to the mammal N-1-butanesulfonamide derivatives and salts | ELI LILLY AND COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0467621-A1 | N-phenyl-N'-alkylsulfonylureas, process for their preparation and antitumor compositions containing them | ELI LILLY AND COMPANY (US) | 1992-01-22 | — | — | EP | disclosed |