Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9612083 | 0.75 | TP53 (0.35) | GRIA4TP53SMN1; SMN2CA12CA2 | |
| SCHEMBL24174300 | 0.71 | — | — | |
| SCHEMBL11707456 | 0.71 | HDAC7 (0.33) | TP53SMN1; SMN2CA12CA2CA9 | |
| SCHEMBL8360658 | 0.71 | GRIA1 (0.39) | GRIA4SMN1; SMN2 | |
| SCHEMBL26879110 | 0.69 | — | — | |
| SCHEMBL16918254 | 0.68 | MMP1 (0.35) | — | |
| SCHEMBL776309 | 0.68 | TP53 (0.41) | TP53SMN1; SMN2CA12CA2CA9 | |
| SCHEMBL24303319 | 0.67 | GRIA1 (0.42) | TP53CA12CA2 | |
| SCHEMBL4851460 | 0.67 | L3MBTL1 (0.34) | — | |
| SCHEMBL19103690 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420409-B1 | GLUCOSE TOLERANCE, DIABETES,INSULIN RESISTANCE, POLYCYSTIC OVARY SYNDROME, HYPERLIPIDEMIA, ATHEROSCLEROSIS, CARDIOVASCULAR DISORDERS, HYPERGLYCEMIA, HYPERTENSION, STENOCARDIA, PULMONARY HYPERTENSION, CONGESTIVE HEART FAILURE, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1020452-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |