SCHEMBL8097752

SCHEMBL8097752

CNc1ccc(OCCO)c(N)c1OC

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 2/20 0.43
DHPS P49366 7/20 0.35
IDO1 P14902 1/20 0.34
ALDH1A1 P00352 3/20 0.34
TSHR P16473 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 1/20 0.34
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9793027 0.80 APP (0.39) TUBB1IDO1ALDH1A1L3MBTL1MEN1
SCHEMBL7238647 0.80 IDO1 (0.35) TUBB1DHPSIDO1ALDH1A1TSHR
Hydrochloric Acid SCHEMBL9793126 0.79 APP (0.38) TUBB1IDO1ALDH1A1L3MBTL1MEN1
SCHEMBL7799801 0.77 ADRA1A (0.35) TUBB1DHPSALDH1A1TSHRMEN1
SCHEMBL22333901 0.73 GAA (0.44) TUBB1IDO1ALDH1A1TSHRMEN1
SCHEMBL7808713 0.72 KDM4E (0.40) TSHRL3MBTL1POLBGAA
SCHEMBL10631959 0.72 TSHR (0.47) TUBB1DHPSALDH1A1TSHRL3MBTL1
SCHEMBL5268545 0.72 IDO1 (0.41) TUBB1IDO1ALDH1A1L3MBTL1MEN1
Hydrochloric Acid SCHEMBL9793192 0.71 KDM4E (0.39) TUBB1ALDH1A1TSHRL3MBTL1POLB
SCHEMBL17998044 0.70 POLB (0.35) TUBB1ALDH1A1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5180397-A Hair dyes L'OREAL (FR) 1993-01-19 US claimed
US-4985955-A INTENSE COLORATIONS IN RELATIVELY SHORT TIMES L'OREAL (FR) 1991-01-22 US claimed
EP-0658339-B1 Process and kit for dyeing hair BRISTOL MYERS SQUIBB CO (US) 2000-06-07 EP disclosed
EP-0658093-B1 PROCESS AND KIT FOR DYEING HAIR BRISTOL MYERS SQUIBB CO (US) 2000-06-07 EP disclosed
US-5628799-A DYE IS A NITROBENZENE SUBSTITUTED WITH AT LEAST ONE NUCLEOPHILIC AMINO GROUP; BUFFER PRESENT; DOPA SPECIES, DYE AND OXIDANT REACT TO FORM MELANIN PRECURSOR WHICH DIFFUSES INTO HAIR TO FORM MELANIN CLAIROL INCORPORATED (US) 1997-05-13 US disclosed
EP-0507448-B1 Oxidative hair dyeing process with catalytic pretreatment BRISTOL MYERS SQUIBB CO (US) 1996-05-29 EP disclosed
EP-0658339-A1 Process and kit for dyeing hair Bristol-Myers Squibb Company (US) 1995-06-21 EP disclosed
EP-0658093-A1 PROCESS AND KIT FOR DYEING HAIR Bristol-Myers Squibb Company (US) 1995-06-21 EP disclosed
US-5376146-A Alkaline aqueous lotion containing primary intermediate and coupler for oxidation dye, quaternary ammonium compound, amphoteric surfactant; acidic aquous developer containing peroxide oxidizer, water insoluble anionic polymer BRISTOL-MYERS SQUIBB COMPANY (US) 1994-12-27 US disclosed
US-5368610-A Use of metal salts and chelates together with chlorites as oxidants in hair coloring CLAIROL INCORPORATED (US) 1994-11-29 US disclosed
EP-0621029-A1 Use of metal salts and chelates together with chlorites as oxidants in hair coloring Bristol-Myers Squibb Company (US) 1994-10-26 EP disclosed
US-5279617-A Using melanin precursor; oxidizing dopa compound with a ferricyanide salt CLAIROL INCORPORATED (US) 1994-01-18 US disclosed
WO-1993005759-A1 PROCESS AND KIT FOR DYEING HAIR BRISTOL-MYERS SQUIBB COMPANY (US) 1993-04-01 WO disclosed
EP-0399746-B1 USE OF CHLORITES AS OXIDANTS IN HAIR COLORING Bristol-Myers Squibb Company (US) 1993-03-10 EP disclosed
US-5180397-A Hair dyes L'OREAL (FR) 1993-01-19 US disclosed
EP-0507448-A2 Oxidative hair dyeing process with catalytic pretreatment Bristol-Myers Squibb Company (US) 1992-10-07 EP disclosed
US-5100436-A Transition metal complex of 2,2*-dipyridine or 1,10-phenanthroline deposited on hair, reduced time for coloring CLAIROL INCORPORATED (US) 1992-03-31 US disclosed
US-5032138-A Chlorites as oxidants in hair coloring CLAIROL INCORPORATED (US) 1991-07-16 US disclosed
US-4985955-A INTENSE COLORATIONS IN RELATIVELY SHORT TIMES L'OREAL (FR) 1991-01-22 US disclosed
EP-0399746-A1 Use of chlorites as oxidants in hair coloring Bristol-Myers Squibb Company (US) 1990-11-28 EP disclosed