Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097874 | 0.81 | MAPT (0.49) | ALDH1A1MAPTHPGDTSHRKMT2A | |
| SCHEMBL8089623 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDTSHRGAA | |
| SCHEMBL8090455 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDTSHRKMT2A | |
| SCHEMBL8089861 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDTSHRKMT2A | |
| SCHEMBL8103622 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDTSHRCYP19A1 | |
| SCHEMBL9389991 | 0.72 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDTSHRCYP19A1 | |
| SCHEMBL8089821 | 0.70 | GFER (0.56) | KMT2AMEN1PBRM1NPC1HPN | |
| SCHEMBL8097598 | 0.69 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDTSHRKMT2A | |
| SCHEMBL6381813 | 0.66 | TDP1 (0.50) | ALDH1A1MAPTKMT2AMEN1PBRM1 | |
| SCHEMBL8922119 | 0.66 | TDP1 (0.50) | ALDH1A1MAPTKMT2AMEN1PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |