Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | TOP2A | P11388 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094753 | 0.89 | KDM4E (0.57) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9046530 | 0.89 | KDM4E (0.46) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8090947 | 0.87 | KDM4E (0.57) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9183483 | 0.86 | KDM4E (0.69) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8673133 | 0.86 | KDM4E (0.59) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8091199 | 0.85 | ALDH1A1 (0.44) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8095031 | 0.85 | DRD3 (0.59) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9665892 | 0.84 | ALDH1A1 (0.72) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8089789 | 0.83 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDHSD17B10TOP2A | |
| SCHEMBL8083243 | 0.82 | DPP4 (0.65) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018054-A | INTERMEDIATE COMPOUNDS FOR PREPARING NOVEL QUINOLONE AND NAPHTHYRIDONE DERIVATIVES WHICH ARE SUBSTITUTED IN THE 7-POSITION BY A PARTIALLY HYDROGENATED ISOINDOLINYL RING, USE AS ANTIBACTERIAL AGENTS AND AS FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-25 | — | — | US | disclosed |
| US-5556979-A | ANIMAL FEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | disclosed |