Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 6/20 | 0.34 |
| ▸ | FNTB | P49356 | 6/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | HAT1 | O14929 | 2/20 | 0.34 |
| ▸ | EP300 | Q09472 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097896 | 1.00 | CYP19A1 (0.38) | CYP19A1CHRM4L3MBTL1HRH3FNTA | |
| SCHEMBL8088328 | 0.96 | CYP19A1 (0.38) | CYP19A1CHRM4L3MBTL1HRH3FNTA | |
| SCHEMBL8088333 | 0.96 | CYP19A1 (0.38) | CYP19A1CHRM4L3MBTL1HRH3FNTA | |
| SCHEMBL8097913 | 0.94 | L3MBTL1 (0.39) | CYP19A1CHRM4L3MBTL1HRH3FNTA | |
| SCHEMBL8101712 | 0.94 | CHRM4 (0.39) | CYP19A1CHRM4L3MBTL1FNTAFNTB | |
| SCHEMBL8097906 | 0.94 | L3MBTL1 (0.39) | CYP19A1CHRM4L3MBTL1HRH3FNTA | |
| SCHEMBL8101707 | 0.94 | CHRM4 (0.39) | CYP19A1CHRM4L3MBTL1FNTAFNTB | |
| SCHEMBL8095938 | 0.93 | CHRM4 (0.37) | CYP19A1CHRM4L3MBTL1HRH3FNTA | |
| SCHEMBL8095934 | 0.93 | CHRM4 (0.37) | CYP19A1CHRM4L3MBTL1HRH3FNTA | |
| SCHEMBL8104371 | 0.90 | CYP19A1 (0.39) | CYP19A1CHRM4L3MBTL1HRH3FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |