Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 2/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107309 | 0.85 | HPGD (0.39) | NPC1SMN1; SMN2HPGDMAPK1KDM4E | |
| SCHEMBL4930687 | 0.76 | — | — | |
| SCHEMBL8097969 | 0.72 | LRRK2 (0.33) | — | |
| SCHEMBL25172614 | 0.72 | KMT2A (0.34) | NPC1RAB9ASMN1; SMN2HPGDCSNK2A1 | |
| SCHEMBL4917812 | 0.72 | MAPT (0.34) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL185541 | 0.71 | KMT2A (0.39) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL14844395 | 0.68 | — | — | |
| SCHEMBL4253734 | 0.66 | CSNK2A1 (0.34) | HPGDCSNK2A1MAPTKDM4EALDH1A1 | |
| SCHEMBL7312275 | 0.65 | KMT2A (0.35) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL16885185 | 0.65 | NUDT1 (0.37) | NPC1RAB9ASMN1; SMN2HPGDCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1091100-C | N-arylsulfilimine compounds and their use as catalysts for the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 2002-09-18 | — | — | CN | disclosed |
| US-6114580-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0888297-B1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-08-30 | — | — | EP | disclosed |
| US-5973148-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 1999-10-26 | — | — | US | disclosed |
| CN-1216040-A | N-arylsulfilimine compounds and their use as catalysts in preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 1999-05-05 | — | — | CN | disclosed |
| EP-0888297-A1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | Dow AgroSciences LLC (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1998021178-A1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 1998-05-22 | — | — | WO | disclosed |