Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | ABL2 | P42684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097976 | 1.00 | ADH1A (0.41) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL6206907 | 0.91 | ADH1A (0.45) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL31238374 | 0.91 | ADH1A (0.45) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL6206911 | 0.91 | ADH1A (0.45) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL6205394 | 0.87 | ADH1A (0.39) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL6205398 | 0.87 | ADH1A (0.39) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL5623925 | 0.84 | ADH1A (0.43) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL5623921 | 0.84 | ADH1A (0.43) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL31237464 | 0.84 | ADH1A (0.43) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL6207802 | 0.81 | ADH1A (0.35) | ADH1AKITFLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130237-A | Condensed N-aclyindoles as antitumor agents | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-10-10 | — | — | US | disclosed |