Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4825547 | 0.83 | TAAR1 (0.49) | KMT2AMEN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL21051622 | 0.78 | USP2 (0.68) | KMT2AALDH1A1SMN1; SMN2PKMUSP2 | |
| SCHEMBL4613052 | 0.77 | MAPT (0.54) | POLBALDH1A1SMN1; SMN2NPC1PKM | |
| SCHEMBL28079639 | 0.76 | ALDH1A1 (0.70) | KMT2AMEN1ALDH1A1HPGDGAA | |
| SCHEMBL8349568 | 0.76 | ALDH1A1 (0.79) | KMT2AMEN1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL28952726 | 0.75 | USP2 (0.64) | KMT2AMEN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL5842906 | 0.75 | USP2 (0.60) | ALDH1A1SMN1; SMN2PKMUSP2GAA | |
| SCHEMBL5842918 | 0.75 | USP2 (0.60) | ALDH1A1SMN1; SMN2PKMUSP2MAPT | |
| SCHEMBL3189768 | 0.75 | SMN1; SMN2 (0.61) | KMT2APOLBALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8393373 | 0.74 | GBA1 (0.60) | KMT2AALDH1A1SMN1; SMN2PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |