Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 10/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096233 | 0.92 | PIK3CD (0.40) | PIK3CDPIK3CAPOLBNAMPT | |
| SCHEMBL8095724 | 0.91 | PIK3CA (0.39) | PIK3CDPIK3CAPOLBNAMPT | |
| SCHEMBL8082658 | 0.89 | PIK3CD (0.39) | PIK3CDPIK3CAPOLBNAMPT | |
| SCHEMBL8089920 | 0.89 | PIK3CD (0.39) | PIK3CDPIK3CAPOLBNAMPT | |
| SCHEMBL8093158 | 0.88 | PIK3CA (0.38) | PIK3CDPIK3CAPOLBNAMPT | |
| SCHEMBL8090187 | 0.88 | PIK3CD (0.42) | PIK3CDPIK3CAPOLB | |
| SCHEMBL8096026 | 0.87 | POLB (0.40) | PIK3CDPIK3CAPOLB | |
| SCHEMBL8099749 | 0.87 | MTOR (0.40) | PIK3CDPIK3CANAMPT | |
| SCHEMBL8098805 | 0.86 | PIK3CD (0.36) | PIK3CDPIK3CAPOLBNAMPT | |
| SCHEMBL8090994 | 0.85 | POLB (0.39) | PIK3CDPIK3CAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007748-A2 | TRISUBSTITUTED PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ASTRAZENECA AB (SE) | 2009-01-15 | — | — | WO | disclosed |