SCHEMBL809831

SCHEMBL809831

FC(F)(c1ccccc1Cl)c1ccccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 3/20 0.48
TSHR P16473 3/20 0.47
LMNA P02545 2/20 0.47
CYP19A1 P11511 3/20 0.42
HSD11B1 P28845 1/20 0.39
ALDH1A1 P00352 2/20 0.38
KCNA3 P22001 2/20 0.36
PDK2 Q15119 2/20 0.35
CYP1A2 P05177 4/20 0.35
HTR2A P28223 2/20 0.35
HTR2C P28335 2/20 0.35
OPRK1 P41145 2/20 0.35
KCNH2 Q12809 2/20 0.35
ADRA1A P35348 1/20 0.35
MEN1 O00255 1/20 0.35
SLC22A1 O15245 1/20 0.35
NR1I2 O75469 1/20 0.35
GMNN O75496 1/20 0.35
USP2 O75604 1/20 0.35
TRPM2 O94759 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5966718 0.83 KCNN4 (0.48) KCNN4TSHRLMNACYP19A1HSD11B1
SCHEMBL117692 0.83 KCNN4 (0.48) KCNN4TSHRLMNACYP19A1HSD11B1
SCHEMBL29467226 0.83 KCNN4 (0.48) KCNN4TSHRLMNACYP19A1HSD11B1
SCHEMBL4463108 0.81 KCNN4 (0.46) KCNN4TSHRLMNACYP19A1HSD11B1
SCHEMBL29057192 0.81 KCNN4 (0.46) KCNN4TSHRLMNACYP19A1HSD11B1
SCHEMBL1117918 0.81 KCNN4 (0.46) KCNN4TSHRLMNACYP19A1HSD11B1
Ammonia Solution, Strong SCHEMBL15562823 0.81 KCNN4 (0.46) KCNN4TSHRLMNACYP19A1HSD11B1
SCHEMBL5607381 0.81 KCNN4 (0.46) KCNN4TSHRLMNACYP19A1HSD11B1
SCHEMBL9491936 0.81 KCNN4 (0.46) KCNN4TSHRLMNACYP19A1HSD11B1
Benzene SCHEMBL29136712 0.81 KCNN4 (0.52) KCNN4TSHRLMNACYP19A1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1693405-B1 PROTON CONDUCTING MEMBRANE AND PROCESS FOR PRODUCING THE SAME JSR CORP (JP) 2012-05-02 EP disclosed
EP-1845122-B1 POLYARYLENE, PROCESS FOR PRODUCING THE SAME, SOLID POLYELECTROLYTE, AND PROTON-CONDUCTIVE FILM JSR CORP (JP) 2011-11-16 EP disclosed
US-8058365-B2 Proton conducting membrane and process for producing the same JSR CORPORATION (JP) 2011-11-15 US disclosed
US-8039165-B2 Proton conductive membrane comprising a copolymer JSR CORPORATION (JP) 2011-10-18 US disclosed
US-7981566-B2 Membrane electrode assembly and polymer electrolyte fuel cell therewith HONDA MOTOR CO., LTD. (JP) 2011-07-19 US disclosed
US-7893303-B2 Polyarylene, process for producing the same, solid polyelectrolyte, and proton-conductive film JSR CORPORATION (JP) 2011-02-22 US disclosed
US-20100190088-A1 MEMBRANE ELECTRODE ASSEMBLY AND POLYMER ELECTROLYTE FUEL CELL THEREWITH HONDA MOTOR CO., LTD. (JP) 2010-07-29 US disclosed
US-7727652-B2 Membrane electrode assembly and polymer electrolyte fuel cell therewith HONDA MOTOR CO., LTD. (JP) 2010-06-01 US disclosed
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
EP-1575115-B1 Polymer electrolyte and proton conductive membrane HONDA MOTOR CO LTD (JP) 2010-02-03 EP disclosed
US-20040043297-A1 Proton conductive resin composition, method for preparing the same, and proton conductive membrane comprising the composition JSR CORPORATION 2004-03-04 US disclosed
EP-1391480-A1 Proton conductive resin composition, method for preparing the same, and proton conductive membrane comprising the composition JSR Corporation (JP) 2004-02-25 EP disclosed
US-20040028806-A1 Process for producing electrolyte membrane-bonded electrode and varnish composition used therein THE RELIABLE AUTOMATIC SPRINKLER CO. INC. 2004-02-12 US disclosed
US-6685984-B2 FORMING FUEL CELL COMPRISED OF NONPENETRATING ELECTROLYTE MEMBRANE ON ELECTRODE JSR CORPORATION (JP) 2004-02-03 US disclosed
US-20030228421-A1 Method for the production of multilayers JSR CORPORATION 2003-12-11 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-20020177656-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORPORATION (JP) 2002-11-28 US disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed
EP-1245554-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR Corporation (JP) 2002-10-02 EP disclosed