Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.45 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.44 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10019208 | 0.87 | FOLH1 (0.46) | FOLH1SLC7A5ANPEPENPEPMAP1LC3B | |
| SCHEMBL765921 | 0.85 | FOLH1 (0.61) | FOLH1ANPEPENPEP | |
| SCHEMBL4054915 | 0.85 | SLC7A5 (0.49) | FOLH1SLC7A5ANPEPENPEPMAP1LC3B | |
| SCHEMBL29478099 | 0.85 | SLC7A5 (0.49) | FOLH1SLC7A5ANPEPENPEPMAP1LC3B | |
| SCHEMBL8100962 | 0.84 | SLC7A5 (0.42) | FOLH1SLC7A5ANPEPENPEP | |
| SCHEMBL11335166 | 0.84 | GSK3B (0.49) | FOLH1SLC7A5ANPEPENPEPMAP1LC3B | |
| SCHEMBL6844044 | 0.84 | FOLH1 (0.55) | FOLH1SLC7A5ANPEPENPEP | |
| SCHEMBL8094952 | 0.84 | FOLH1 (0.46) | FOLH1SLC7A5ANPEPENPEPMAP1LC3B | |
| SCHEMBL28403219 | 0.82 | SLC7A5 (0.54) | FOLH1SLC7A5ANPEPENPEPMAP1LC3B | |
| SCHEMBL6072390 | 0.82 | ATM (0.57) | FOLH1SLC7A5HSD17B10GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |