SCHEMBL809842

SCHEMBL809842

N#CN=C(N)N(CC1CCC(CN(C(N)=NC#N)c2ccncc2)CC1)c1ccncc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLG P00747 1/20 0.31
ACHE P22303 1/20 0.31
F2 P00734 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL810674 0.78 PLG (0.33) PLG
SCHEMBL809997 0.78 PLG (0.33) PLG
SCHEMBL10338064 0.73 LMNA (0.32)
SCHEMBL8195686 0.70 KDM4E (0.30)
SCHEMBL504564 0.69 PLG (0.41) PLGF2
SCHEMBL13277041 0.69 NAMPT (0.43)
SCHEMBL13277354 0.69 NAMPT (0.43)
SCHEMBL13277914 0.69 NAMPT (0.43)
SCHEMBL13277397 0.68 NAMPT (0.33)
SCHEMBL13277115 0.68 NAMPT (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2394649-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING PYRIDYL CYANOGUANIDINES, PREPARATION METHODS AND USES THEREOF Tianjin Hemay Bio-Tech Co., Ltd. (CN) 2011-12-14 EP disclosed