Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098507 | 1.00 | ALDH1A1 (0.52) | ALDH1A1HCAR2THRBTSHRNPSR1 | |
| SCHEMBL15201368 | 0.89 | ALDH1A1 (0.50) | ALDH1A1HCAR2THRBTSHRNPSR1 | |
| Ethyl Fumarate SCHEMBL1066994 | 0.85 | HCAR2 (0.67) | ALDH1A1HCAR2THRBTSHRNPSR1 | |
| SCHEMBL15201468 | 0.83 | ALDH1A1 (0.62) | ALDH1A1HCAR2THRBTSHRMAPT | |
| Acrylic Acid Ethyl Ester SCHEMBL27286743 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HCAR2THRBTSHRNPSR1 | |
| Acrylic Acid Ethyl Ester SCHEMBL4889568 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HCAR2THRBTSHRNPSR1 | |
| Acrylic Acid Ethyl Ester SCHEMBL5959889 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HCAR2THRBTSHRNPSR1 | |
| Acrylic Acid Ethyl Ester SCHEMBL2097752 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HCAR2THRBTSHRNPSR1 | |
| Acrylic Acid Ethyl Ester SCHEMBL146757 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HCAR2THRBTSHRNPSR1 | |
| Acrylic Acid Ethyl Ester SCHEMBL29246428 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HCAR2THRBTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066702-A | AN ALPHA-OLEFIN IS POLYMERIZED OR COPOLYMERIZED USING, AS EXTERNAL ELECTRON DONORS, THREE KINDS OF ORGANOSILICON COMPOUNDS, A SOLID COMPLEX TITANUM HALIDE, MAGESIUM COMPOUND, AN INTERNAL ELECTRON DONOR AND AN ORGANOMETALLIC COMPOUND | SAMSUNG GENERAL CHEMICALS CO., LTD. (CN) | 2000-05-23 | — | — | US | disclosed |