Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067128 | 0.87 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL8080218 | 0.86 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL6993939 | 0.83 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL8076957 | 0.81 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL8067255 | 0.81 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL8067146 | 0.81 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL8076878 | 0.81 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL8077224 | 0.81 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL8098679 | 0.80 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL8076981 | 0.80 | PTGS2 (0.75) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6133292-A | NON-STEROIDAL ANTIINFLAMMATORY DRUG, INHIBIT HORMONE-INDUCED UTERINE CONTRACTIONS, ANTICARCINOGENIC AGENTS, ANTIPYRETICS; ANALGESICS; SIDE EFFECT REDUCTION; PREVENT THE SYNTHESIS OF CONTRACTILE PROSTANOIDS, DYSMENORRHEA, ASTHMA | MERCK FROSST CANADA & CO. (CA) | 2000-10-17 | — | — | US | claimed |
| US-6133292-A | NON-STEROIDAL ANTIINFLAMMATORY DRUG, INHIBIT HORMONE-INDUCED UTERINE CONTRACTIONS, ANTICARCINOGENIC AGENTS, ANTIPYRETICS; ANALGESICS; SIDE EFFECT REDUCTION; PREVENT THE SYNTHESIS OF CONTRACTILE PROSTANOIDS, DYSMENORRHEA, ASTHMA | MERCK FROSST CANADA & CO. (CA) | 2000-10-17 | — | — | US | disclosed |