Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8138248 | 0.87 | LMNA (0.40) | LMNACA12CA1CA2CA3 | |
| SCHEMBL8139387 | 0.84 | LMNA (0.41) | LMNACA12CA1CA2CA3 | |
| SCHEMBL8145443 | 0.84 | CHRM2 (0.43) | LMNACA12CA1CA2CA3 | |
| SCHEMBL8138231 | 0.82 | CHRM2 (0.39) | LMNACA12CA1CA2CA3 | |
| SCHEMBL8149843 | 0.82 | LMNA (0.42) | LMNACA12CA1CA2CA3 | |
| SCHEMBL8140650 | 0.82 | LMNA (0.42) | LMNACA12CA1CA2CA3 | |
| SCHEMBL2382699 | 0.81 | LMNA (0.45) | LMNACA12CA1CA2CA3 | |
| SCHEMBL8155612 | 0.79 | LMNA (0.46) | LMNACA12CA1CA2CA3 | |
| SCHEMBL4195230 | 0.77 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL7782423 | 0.77 | LMNA (0.47) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020449-A | Alkoxy-crosslinking RTV1 silicone rubber mixtures | WACKER-CHEMIE GMBH (DE) | 2000-02-01 | — | — | US | claimed |
| US-6020448-A | N-[ω-(methyl),ω-(silyl)] alkyl-N-organocarboxamides, oligomeric and polycondensed Si-containing compounds thereof, processes for their preparation, and their use | HUELS AKTIENGESELLSCHAFT (DE) | 2000-02-01 | — | — | US | disclosed |
| US-6018011-A | OBTAINED BY REACTING A POLYORGANOSILOXANE, WITH A REACTION PRODUCT OF AN ORGANOSILANE OF GIVEN FORMULA AND N-1-((METHYLDIETHOXYSILOXY)DIETHOXYSILYL)ETHYL-2-PYRROLIDONE; USE IN ALKOXY-CROSSLINKING RTV SILICONE RUBBER MIXTURES | HUELS SILICONE GMBH (DE) | 2000-01-25 | — | — | US | disclosed |
| US-6001948-A | BASED ON HYDROXY-TERMINATED POLYDIORGANOSILOXANES CONTAINING A TRIALKOXYSILANE WITH A SUBSTITUTED AMIDOALKYL RADICAL, WHICH CAN BE PREPARED USING CONVENTIONAL MIXING TECHNOLOGIES. | WACKER-CHEMIE GMBH (DE) | 1999-12-14 | — | — | US | disclosed |
| EP-0885931-A2 | One-component alkoxy group containing RTV-systems | Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-4404306-A | Blends of water reducible organic materials and aqueous metal ammine siliconate solutions | DOW CORNING CORPORATION (US) | 1983-09-13 | — | — | US | disclosed |
| US-4404196-A | Antimicrobial ointment | DOW CORNING CORPORATION (US) | 1983-09-13 | — | — | US | disclosed |
| US-4400326-A | Aqueous metal ammine siliconate solutions, and amorphous materials derived therefrom, and methods of their use | DOW CORNING CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
| US-4377608-A | Method of modifying a substrate | DOW CORNING CORPORATION (US) | 1983-03-22 | — | — | US | disclosed |