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SCHEMBL8098615

SCHEMBL8098615

COC(=O)C[C@@H](O)[C@@H]1C[C@@H](O[Si](C)(C)C(C)(C)C)CN1C(=O)OC(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ABCB1 P08183 1/20 0.31
▸ NR1H2 P55055 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8112292 1.00 ABCB1 (0.31) ABCB1NR1H2
SCHEMBL8106565 1.00 ABCB1 (0.31) ABCB1NR1H2
SCHEMBL8108016 0.93 NR1H2 (0.32) NR1H2
SCHEMBL8106371 0.89 SRC (0.31) NR1H2
SCHEMBL8106388 0.89 NR1H2 (0.31) NR1H2
SCHEMBL8106777 0.89 NR1H2 (0.31) NR1H2
SCHEMBL8106756 0.89 NR1H2 (0.31) NR1H2
SCHEMBL8107979 0.86 NR1H2 (0.36) NR1H2
SCHEMBL9595771 0.86 NR1H2 (0.36) NR1H2
SCHEMBL8106571 0.85 NR1H2 (0.35) NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545290-B1 Aminoalkylpyrrolidinylthiocarbapenem derivatives BANYU PHARMA CO LTD (JP) 2000-08-23 — — EP disclosed
US-5550121-A ANTIBIOTICS BANYU PHARMACEUTICAL CO., LTD. (JP) 1996-08-27 — — US disclosed
WO-1993011128-A1 AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-06-10 — — WO disclosed
EP-0545290-A1 Aminoalkylpyrrolidinylthiocarbapenem derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-06-09 — — EP disclosed
WO-1993001174-A1 THIAZOLIDINE DERIVATIVES AND THEIR USE AS ANTI-VIRAL COMPOUNDS GLAXO GROUP LIMITED (GB) 1993-01-21 — — WO disclosed