Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12816215 | 0.79 | INMT (0.53) | INMTUSP2CHRM3PDE4APDE4B | |
| SCHEMBL22097724 | 0.72 | CHRM3 (0.30) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25772795 | 0.69 | SMN1; SMN2 (0.39) | INMTUSP2NOS3NOS1NOS2 | |
| SCHEMBL6859068 | 0.68 | INMT (0.39) | INMTUSP2CHRM3PDE4APDE4B | |
| SCHEMBL6860529 | 0.67 | INMT (0.47) | INMTUSP2CHRM3PDE4APDE4B | |
| SCHEMBL22193156 | 0.66 | INMT (0.59) | INMTUSP2 | |
| SCHEMBL6859941 | 0.65 | INMT (0.50) | INMTUSP2CHRM3PDE4APDE4B | |
| SCHEMBL2927 | 0.64 | — | — | |
| SCHEMBL9387445 | 0.64 | — | — | |
| SCHEMBL17417845 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019174607-A1 | DIHYDROPYRIDOPHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海艾力斯医药科技有限公司 | 2019-09-19 | — | — | WO | disclosed |
| EP-2098567-B1 | ACRYLIC RUBBER COMPOSITION AND VULCANIZATE THEREOF | DENKI KAGAKU KOGYO KK (JP) | 2011-11-16 | — | — | EP | disclosed |
| US-8012556-B2 | Acrylic rubber composition and its vulcanized product | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20100009105-A1 | ACRYLIC RUBBER COMPOSITION AND VULCANIZED PRODUCT | DENKI KAGAKU KIGYO KABUSHIKI KAISHA (JP) | 2010-01-14 | — | — | US | disclosed |
| EP-2098567-A1 | ACRYLIC RUBBER COMPOSITION AND VULCANIZATE THEREOF | Denki Kagaku Kogyo Kabushiki Kaisha (JP) | 2009-09-09 | — | — | EP | disclosed |