Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648529 | 0.87 | ALDH1A1 (0.30) | TSHRALDH1A1TDP1 | |
| Methylene Chloride SCHEMBL4978044 | 0.80 | — | — | |
| Butane SCHEMBL2191135 | 0.80 | — | — | |
| Butane SCHEMBL5143505 | 0.78 | — | — | |
| SCHEMBL648363 | 0.76 | — | — | |
| SCHEMBL61348 | 0.76 | — | — | |
| Bromoethane SCHEMBL9585555 | 0.74 | — | — | |
| SCHEMBL6916454 | 0.74 | — | — | |
| SCHEMBL1081411 | 0.74 | TSHR (0.31) | TSHRTHRB | |
| SCHEMBL8167046 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127305-A | Catalyst and process for polymerizing alpha-olefins | ENICHEM S.P.A (IT) | 2000-10-03 | — | — | US | claimed |
| EP-0588404-B1 | Catalyst and process for polymerizing alpha-olefins | ENICHEM SPA (IT) | 1997-06-18 | — | — | EP | claimed |
| EP-0588404-A2 | Catalyst and process for polymerizing alpha-olefins | ENICHEM S.p.A. (IT) | 1994-03-23 | — | — | EP | claimed |
| EP-0422703-B1 | CATALYST AND PROCESS FOR THE POLYMERIZATION AND COPOLYMERIZATION OF ALPHA-OLEFINS | Enichem Anic S.r.l. (IT) | 1993-06-30 | — | — | EP | claimed |
| US-5128295-A | Hafnium-titanium-zirconium compound with trialkylaluminum and distannoxane | ENICHEM ANIC S.P.A. (IT) | 1992-07-07 | — | — | US | claimed |
| EP-0422703-A1 | Catalyst and process for the polymerization and copolymerization of alpha-olefins | Enichem Anic S.r.l. (IT) | 1991-04-17 | — | — | EP | claimed |
| US-6127305-A | Catalyst and process for polymerizing alpha-olefins | ENICHEM S.P.A (IT) | 2000-10-03 | — | — | US | disclosed |
| EP-0588404-B1 | Catalyst and process for polymerizing alpha-olefins | ENICHEM SPA (IT) | 1997-06-18 | — | — | EP | disclosed |
| EP-0588404-A2 | Catalyst and process for polymerizing alpha-olefins | ENICHEM S.p.A. (IT) | 1994-03-23 | — | — | EP | disclosed |
| EP-0422703-B1 | CATALYST AND PROCESS FOR THE POLYMERIZATION AND COPOLYMERIZATION OF ALPHA-OLEFINS | Enichem Anic S.r.l. (IT) | 1993-06-30 | — | — | EP | disclosed |
| US-5128295-A | Hafnium-titanium-zirconium compound with trialkylaluminum and distannoxane | ENICHEM ANIC S.P.A. (IT) | 1992-07-07 | — | — | US | disclosed |
| EP-0422703-A1 | Catalyst and process for the polymerization and copolymerization of alpha-olefins | Enichem Anic S.r.l. (IT) | 1991-04-17 | — | — | EP | disclosed |