Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 12/20 | 0.90 |
| ▸ | EGFR | P00533 | 4/20 | 0.73 |
| ▸ | ABL1 | P00519 | 3/20 | 0.73 |
| ▸ | ABL2 | P42684 | 3/20 | 0.73 |
| ▸ | RIPK2 | O43353 | 8/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098911 | 0.95 | SRC (1.00) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL28667953 | 0.92 | SRC (0.79) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL8107053 | 0.91 | SRC (0.90) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL30054291 | 0.91 | SRC (0.78) | SRCEGFRABL1ABL2 | |
| SCHEMBL6462070 | 0.91 | SRC (0.78) | SRCEGFRABL1ABL2 | |
| SCHEMBL13020336 | 0.90 | SRC (0.76) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL8098919 | 0.90 | SRC (0.90) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL8108104 | 0.90 | SRC (0.91) | SRCEGFRABL1ABL2 | |
| SCHEMBL7021401 | 0.88 | SRC (0.73) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL18653507 | 0.88 | SRC (0.73) | SRCEGFRABL1ABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051577-A | TYROSINE INHIBITORS; BONE DISORDERS | NOVARTIS AG (CH) | 2000-04-18 | — | — | US | disclosed |