Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.40 |
| ▸ | RXRA | P19793 | 4/20 | 0.40 |
| ▸ | RXRB | P28702 | 3/20 | 0.40 |
| ▸ | RXRG | P48443 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 4/20 | 0.33 |
| ▸ | RARG | P13631 | 4/20 | 0.33 |
| ▸ | RARA | P10276 | 3/20 | 0.33 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801863 | 0.90 | RXRA (0.48) | CYP3A4CYP26A1RXRARXRBRXRG | |
| SCHEMBL8101865 | 0.90 | CYP3A4 (0.54) | CYP3A4CYP26A1RXRARXRBRXRG | |
| SCHEMBL8099280 | 0.87 | RXRA (0.43) | CYP3A4CYP26A1RXRARXRBRXRG | |
| SCHEMBL8086349 | 0.81 | CYP3A4 (0.45) | CYP3A4CYP26A1RXRARXRBRXRG | |
| SCHEMBL8086450 | 0.80 | CYP3A4 (0.47) | CYP3A4CYP26A1RXRARXRBRXRG | |
| SCHEMBL8094159 | 0.80 | CYP3A4 (0.56) | CYP3A4CYP26A1RXRARXRBRXRG | |
| SCHEMBL7802940 | 0.80 | CYP26A1 (0.53) | CYP3A4CYP26A1RXRARXRBRXRG | |
| SCHEMBL7799981 | 0.77 | RXRA (0.51) | CYP3A4CYP26A1RXRARXRBRXRG | |
| SCHEMBL6733878 | 0.77 | CYP3A4 (0.71) | CYP3A4CYP26A1RXRARXRBRXRG | |
| SCHEMBL20876235 | 0.76 | MAPT (0.46) | MGLLALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030952-A | AS HUMAN AND VETERINARY MEDICINE, PARTICULARLY IN THE TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR AND OPHTHALMOLOGIC CONDITIONS, AND IN COSMETIC COMPOSITIONS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIOUES GALDERMA (FR) | 2000-02-29 | — | — | US | disclosed |