SCHEMBL8099520

SCHEMBL8099520

CCCCCN(C)CCc1ccccc1

nearest known ligand 0.96

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 8/20 0.76
EBP Q15125 1/20 0.59
KCNH2 Q12809 1/20 0.59
THRA P10827 1/20 0.58
THRB P10828 1/20 0.58
TAAR1 Q96RJ0 1/20 0.55
DRD2 P14416 2/20 0.54
OPRM1 P35372 2/20 0.54
DRD3 P35462 2/20 0.54
OPRD1 P41143 2/20 0.54
OPRK1 P41145 2/20 0.54
SLC6A2 P23975 1/20 0.54
SLC6A4 P31645 1/20 0.54
SLC6A3 Q01959 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9392475 0.98 SIGMAR1 (0.79) SIGMAR1EBPKCNH2THRATHRB
SCHEMBL27611325 0.98 SIGMAR1 (0.79) SIGMAR1EBPKCNH2THRATHRB
SCHEMBL10802386 0.98 SIGMAR1 (0.79) SIGMAR1EBPKCNH2THRATHRB
SCHEMBL9377824 0.96 SIGMAR1 (0.77) SIGMAR1EBPKCNH2THRATHRB
Hydrochloric Acid SCHEMBL28021779 0.95 SIGMAR1 (0.74) SIGMAR1EBPKCNH2THRATHRB
SCHEMBL11922685 0.94 SIGMAR1 (0.72) SIGMAR1EBPTHRATHRBTAAR1
SCHEMBL11567562 0.91 SIGMAR1 (0.86) SIGMAR1EBPKCNH2THRATHRB
SCHEMBL11130673 0.91 SIGMAR1 (0.86) SIGMAR1EBPKCNH2THRATHRB
SCHEMBL29107028 0.91 SIGMAR1 (0.82) SIGMAR1EBPKCNH2THRATHRB
SCHEMBL11131202 0.91 SIGMAR1 (0.82) SIGMAR1EBPKCNH2THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6057371-A TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, GASTROINTESTINAL DISORDERS, DRUG ABUSE, ANGINA, MIGRAINE, HYPERTENSION AND DEPRESSION VIRGINIA COMMONWEALTH UNIVERSITY (US) 2000-05-02 US claimed
EP-0591426-A1 SIGMA RECEPTOR LIGANDS AND THE USE THEREOF VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-04-13 EP claimed
WO-1993000313-A2 SIGMA RECEPTOR LIGANDS AND THE USE THEREOF VIRGINIA COMMONWEALTH UNIVERSITY (US) 1993-01-07 WO claimed
EP-3898299-B1 VAPOR AND PARTICULATE SENSOR SYSTEM FOR AUTOMOTIVE VEHICLES GENTEX CORP (US) 2025-11-19 EP disclosed
EP-4058780-B1 SYSTEM AND METHODS FOR CHEMICAL DETECTION AND AMPLIFICATION GENTEX CORP (US) 2025-03-26 EP disclosed
US-11796523-B2 Vapor and particulate sensor system for aerospace GENTEX CORPORATION (US) 2023-10-24 US disclosed
US-11458805-B2 Vapor and particulate sensor system for automotive vehicles GENTEX CORPORATION (US) 2022-10-04 US disclosed
EP-4058780-A1 SYSTEM AND METHODS FOR CHEMICAL DETECTION AND AMPLIFICATION GENTEX CORPORATION (US) 2022-09-21 EP disclosed
US-11423761-B2 Connected monitoring system GENTEX CORPORATION (US) 2022-08-23 US disclosed
EP-4028756-A1 VAPOR AND PARTICULATE SENSOR SYSTEM FOR AEROSPACE GENTEX CORPORATION (US) 2022-07-20 EP disclosed
US-11181497-B2 System and methods for chemical detection and amplification GENTEX CORPORATION (US) 2021-11-23 US disclosed
US-20210116432-A1 VAPOR AND PARTICULATE SENSOR SYSTEM FOR AEROSPACE GENTEX CORPORATION 2021-04-22 US disclosed
US-20200202148-A1 SYSTEMS AND METHODS FOR RIDE SHARE MONITORING GENTEX CORPORATION (US) 2020-06-25 US disclosed
US-20200198436-A1 VAPOR AND PARTICULATE SENSOR SYSTEM FOR AUTOMOTIVE VEHICLES GENTEX CORPORATION (US) 2020-06-25 US disclosed
WO-2020128923-A1 VAPOR AND PARTICULATE SENSOR SYSTEM FOR AUTOMOTIVE VEHICLES GENTEX CORPORATION (US) 2020-06-25 WO disclosed
WO-2020128921-A1 SYSTEMS AND METHODS FOR RIDE SHARE MONITORING GENTEX CORPORATION (US) 2020-06-25 WO disclosed
EP-1467974-B1 BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS GNRH ANTAGONISTS SOD CONSEILS RECH APPLIC (FR) 2007-08-15 EP disclosed
US-6057371-A TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, GASTROINTESTINAL DISORDERS, DRUG ABUSE, ANGINA, MIGRAINE, HYPERTENSION AND DEPRESSION VIRGINIA COMMONWEALTH UNIVERSITY (US) 2000-05-02 US disclosed
EP-0591426-A1 SIGMA RECEPTOR LIGANDS AND THE USE THEREOF VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-04-13 EP disclosed
WO-1993000313-A2 SIGMA RECEPTOR LIGANDS AND THE USE THEREOF VIRGINIA COMMONWEALTH UNIVERSITY (US) 1993-01-07 WO disclosed