Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13945377 | 0.93 | CCR3 (0.47) | CHRM4ALDH1A1CCR3KCNH2HRH1 | |
| SCHEMBL8097730 | 0.86 | GAA (0.45) | CHRM4ALDH1A1CCR3KCNH2HRH1 | |
| SCHEMBL13945459 | 0.86 | ALDH1A1 (0.47) | CHRM4ALDH1A1CCR3HRH1ATM | |
| SCHEMBL13969213 | 0.85 | GAA (0.42) | CHRM4ALDH1A1CCR3KCNH2HRH1 | |
| SCHEMBL13945372 | 0.83 | SMN1; SMN2 (0.52) | CHRM4ALDH1A1HTR1D | |
| SCHEMBL8088928 | 0.83 | HRH1 (0.48) | ALDH1A1CCR3KCNH2HRH1HCRTR1 | |
| SCHEMBL4242392 | 0.82 | CHRM4 (0.49) | CHRM4CCR3KCNH2HRH1OPRK1 | |
| SCHEMBL4245783 | 0.79 | CCR3 (0.45) | CCR3KCNH2HRH1RBP4TTR | |
| SCHEMBL4242109 | 0.78 | CHRM4 (0.40) | CHRM4GRM2OPRK1HTR1D | |
| SCHEMBL8091662 | 0.78 | HRH1 (0.47) | ALDH1A1CCR3KCNH2HRH1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000085-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES USEFUL AS MODULATORS OF GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-12-31 | — | — | WO | disclosed |