SCHEMBL8100402

SCHEMBL8100402

CCC(CC)(NC(=O)C(C)c1ccc(Cl)cc1)C(N)=O

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 3/20 0.43
L3MBTL1 Q9Y468 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39
TRPV1 Q8NER1 1/20 0.39
TSHR P16473 1/20 0.38
CXCR1 P25024 1/20 0.38
CXCR2 P25025 1/20 0.38
CHRM1 P11229 1/20 0.38
PDE4A P27815 1/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
WDR5 P61964 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8106481 0.84 FFAR2 (0.42) FFAR2L3MBTL1HDAC4HDAC7HDAC5
SCHEMBL6195873 0.74 TSHR (0.59) FFAR2HDAC4HDAC7HDAC5TRPV1
SCHEMBL7220062 0.73 MEN1 (0.43) FFAR2L3MBTL1HDAC4HDAC7HDAC5
SCHEMBL26955949 0.72 FFAR2 (0.68) FFAR2HDAC4HDAC7HDAC5TRPV1
SCHEMBL7220058 0.72 FFAR2 (0.44) FFAR2HDAC4HDAC7HDAC5TRPV1
SCHEMBL7638474 0.72 FFAR2 (0.44) FFAR2HDAC4HDAC7HDAC5TRPV1
SCHEMBL8104975 0.72 FFAR2 (0.44) FFAR2HDAC4HDAC7HDAC5TRPV1
SCHEMBL7794207 0.71 EPHX1 (0.58) FFAR2HDAC4HDAC7HDAC5TSHR
SCHEMBL607802 0.71 EPHX1 (0.58) FFAR2HDAC4HDAC7HDAC5TSHR
SCHEMBL607803 0.71 EPHX1 (0.58) FFAR2HDAC4HDAC7HDAC5TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6075055-A EXCELLENT FUNGICIDAL ACTIVITIES WITH REGARD TO RICE BLAST AND THE LIKE, WHILE AT THE SAME TIME DO NOT HINDER DESIRABLE PLANT GROWTH KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2000-06-13 US disclosed
EP-0854134-B1 PHENYLALKANAMIDE DERIVATIVES AND AGROHORTICULTURAL BACTERICIDES KUMAII CHEMICAL INDUSTRY CO LT (JP) 2000-04-26 EP disclosed
EP-0854134-A1 PHENYLALKANAMIDE DERIVATIVES AND AGROHORTICULTURAL BACTERICIDES KumaiI Chemical Industry Co., Ltd. (JP) 1998-07-22 EP disclosed