Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208804 | 1.00 | ADORA2A (0.65) | ADORA2AADORA1ADORA3ADORA2B | |
| Formic Acid SCHEMBL7208261 | 0.96 | ADORA2A (0.60) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7208270 | 0.90 | ADORA2A (0.55) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7208265 | 0.88 | ADORA2A (0.53) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7204932 | 0.84 | ADORA2A (0.51) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL2776512 | 0.82 | ADORA2A (0.75) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL6574959 | 0.82 | ADORA3 (0.62) | ADORA2AADORA1ADORA3ADORA2B | |
| Formic Acid SCHEMBL7574645 | 0.81 | ADORA2A (0.49) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL8091540 | 0.80 | ADORA2A (0.65) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7203902 | 0.80 | ADORA2A (0.65) | ADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056759-A1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-12-06 | — | — | EP | claimed |
| WO-1999041267-A1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-08-19 | — | — | WO | claimed |