Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869677 | 1.00 | SIGMAR1 (0.59) | SIGMAR1TMEM97ADRA2AADRA2BADRA2C | |
| SCHEMBL8109911 | 0.99 | SIGMAR1 (0.60) | SIGMAR1TMEM97ADRA2AADRA2BADRA2C | |
| SCHEMBL8116414 | 0.92 | SIGMAR1 (0.60) | SIGMAR1TMEM97ADRA2AADRA2BADRA2C | |
| SCHEMBL8870613 | 0.92 | SIGMAR1 (0.60) | SIGMAR1TMEM97ADRA2AADRA2BADRA2C | |
| SCHEMBL8116630 | 0.91 | SIGMAR1 (0.58) | SIGMAR1TMEM97ADRA2AADRA2BADRA2C | |
| SCHEMBL8948259 | 0.86 | SIGMAR1 (0.68) | SIGMAR1TMEM97ADRA2AADRA2BADRA2C | |
| SCHEMBL8109892 | 0.85 | SIGMAR1 (0.55) | SIGMAR1TMEM97 | |
| SCHEMBL8948162 | 0.85 | SIGMAR1 (0.69) | SIGMAR1TMEM97ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL8871344 | 0.84 | SIGMAR1 (0.54) | SIGMAR1TMEM97 | |
| SCHEMBL9437770 | 0.83 | SIGMAR1 (0.54) | SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673933-B1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR (FR) | 2000-11-08 | — | — | EP | disclosed |
| US-5688820-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-11-18 | — | — | US | disclosed |
| US-5688811-A | PSYCHOLOGICAL DISORDERS; NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-11-18 | — | — | US | disclosed |
| US-5534511-A | AFFINITY FOR SIGMA RECEPTORS, ANTIINFLAMMATORY, TREATMENT OF ARTHRITIS | ADIR ET COMPAGNIE (FR) | 1996-07-09 | — | — | US | disclosed |
| EP-0673933-A1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |