Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093354 | 1.00 | PTGS2 (0.46) | PTGS2MAOBPTGS1AKR1C3AKR1C2 | |
| SCHEMBL8438289 | 1.00 | PTGS2 (0.46) | PTGS2MAOBPTGS1AKR1C3AKR1C2 | |
| SCHEMBL8106460 | 0.88 | CA1 (0.53) | PTGS2MAOBPTGS1KMT2ACA12 | |
| SCHEMBL8093790 | 0.88 | CA1 (0.53) | PTGS2MAOBPTGS1KMT2ACA12 | |
| SCHEMBL8106457 | 0.88 | CA1 (0.53) | PTGS2MAOBPTGS1KMT2ACA12 | |
| SCHEMBL8092672 | 0.87 | PTGS2 (0.43) | PTGS2MAOBPTGS1KMT2A | |
| SCHEMBL8094120 | 0.86 | PTGS2 (0.46) | PTGS2PTGS1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL8441150 | 0.86 | PTGS2 (0.46) | PTGS2PTGS1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL8441152 | 0.86 | PTGS2 (0.46) | PTGS2PTGS1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL8088351 | 0.84 | PTGS2 (0.42) | PTGS2MAOBPTGS1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058682-A1 | HETEROCYCLIC DIARYLMETHYLENE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USES IN THERAPEUTICS | LABORATOIRES UPSA (FR) | 2000-12-13 | — | — | EP | disclosed |
| US-6004994-A | ANTIINFLAMMATORY AGENTS, CYCLOOXYGENASE INHIBITORS AND ANALGESICS | LABORATOIRES UPSA (FR) | 1999-12-21 | — | — | US | disclosed |
| WO-1999043664-A1 | HETEROCYCLIC DIARYLMETHYLENE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USES IN THERAPEUTICS | LABORATOIRES UPSA (FR) | 1999-09-02 | — | — | WO | disclosed |