Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18244757 | 0.83 | ATM (0.42) | TTPAALOX5PSEN1 | |
| SCHEMBL18789245 | 0.78 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL15106146 | 0.72 | PTGS1 (0.39) | PSEN1 | |
| SCHEMBL8108521 | 0.70 | PSEN1 (0.30) | PSEN1 | |
| SCHEMBL21803156 | 0.67 | ATM (0.44) | — | |
| Bromide SCHEMBL21834016 | 0.65 | ATM (0.42) | — | |
| SCHEMBL5789967 | 0.64 | BCHE (0.37) | — | |
| SCHEMBL21834015 | 0.63 | ATM (0.40) | — | |
| SCHEMBL18252889 | 0.62 | ATM (0.39) | — | |
| SCHEMBL20625157 | 0.62 | KCNA3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136986-A | REACTING SUBSTITUTED ACROLEIN COMPOUND WITH ACRYLATES, ACROLEINS, ACROLEIN ACETALS, ALLYL ALCOHOLS OR ALLYL ETHERS TO GIVE 3,4-DIHYDRO-2H-PYRANS, REACTING WITH ACID, FOLLOWED BY REACTING WITH SUBSTITUETED VINYL KETONE, DEHYDROGENATION | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |