Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108583 | 0.88 | PSEN1 (0.31) | PSEN1 | |
| SCHEMBL7563288 | 0.81 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL8100696 | 0.70 | TTPA (0.33) | PSEN1 | |
| SCHEMBL7561746 | 0.62 | — | — | |
| SCHEMBL5789967 | 0.61 | BCHE (0.37) | — | |
| SCHEMBL7921660 | 0.57 | PSEN1 (0.39) | PSEN1 | |
| SCHEMBL25061757 | 0.57 | PSEN1 (0.32) | PSEN1 | |
| SCHEMBL24500903 | 0.57 | MAPT (0.37) | — | |
| SCHEMBL24802589 | 0.56 | BRD4 (0.37) | — | |
| SCHEMBL31693652 | 0.56 | CYP1A2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136986-A | REACTING SUBSTITUTED ACROLEIN COMPOUND WITH ACRYLATES, ACROLEINS, ACROLEIN ACETALS, ALLYL ALCOHOLS OR ALLYL ETHERS TO GIVE 3,4-DIHYDRO-2H-PYRANS, REACTING WITH ACID, FOLLOWED BY REACTING WITH SUBSTITUETED VINYL KETONE, DEHYDROGENATION | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |