Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100940 | 0.90 | FFAR1 (0.55) | FFAR1AKR1B1ALDH1A1HPGDTSHR | |
| SCHEMBL8099277 | 0.84 | FFAR1 (0.57) | FFAR1AKR1B1ALDH1A1HPGDESR2 | |
| SCHEMBL6961627 | 0.79 | ESR2 (0.51) | FFAR1AKR1B1ALDH1A1HPGDTSHR | |
| SCHEMBL6959613 | 0.79 | ESR2 (0.51) | FFAR1AKR1B1ALDH1A1HPGDESR2 | |
| SCHEMBL6960961 | 0.79 | ESR2 (0.54) | FFAR1AKR1B1ALDH1A1HPGDESR2 | |
| SCHEMBL8101456 | 0.77 | NPC1 (0.53) | FFAR1AKR1B1ALDH1A1ESR2PTPN1 | |
| SCHEMBL11573789 | 0.77 | KDM4E (0.52) | FFAR1AKR1B1ALDH1A1HPGDESR2 | |
| SCHEMBL9634048 | 0.76 | KDM4E (0.54) | FFAR1AKR1B1ALDH1A1HPGDTSHR | |
| SCHEMBL4257509 | 0.76 | KDM4E (0.54) | FFAR1AKR1B1ALDH1A1HPGDTSHR | |
| SCHEMBL6957583 | 0.74 | ESR2 (0.56) | FFAR1AKR1B1ALDH1A1HPGDESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117885-A | Biphenyl-substituted quinoline derivatives | E. R. SQUIBB & SONS, INC. (US) | 2000-09-12 | — | — | US | disclosed |
| EP-0556060-A1 | Biphenyl-substituted quinoline and naphthyridines derivatives as angiotensine II antagonists | E.R. SQUIBB & SONS, INC. (US) | 1993-08-18 | — | — | EP | disclosed |