Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.64 |
| ▸ | CDC25B | P30305 | 1/20 | 0.64 |
| ▸ | OSBP | P22059 | 3/20 | 0.52 |
| ▸ | OSBP2 | Q969R2 | 3/20 | 0.52 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.49 |
| ▸ | GPR183 | P32249 | 3/20 | 0.49 |
| ▸ | VDR | P11473 | 3/20 | 0.47 |
| ▸ | CRYAB | P02511 | 1/20 | 0.47 |
| ▸ | HMGCR | P04035 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8503731 | 1.00 | CDC25A (0.64) | CDC25ACDC25BOSBPOSBP2NPC1L1 | |
| SCHEMBL26322309 | 0.94 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2NPC1L1 | |
| SCHEMBL17888102 | 0.94 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2NPC1L1 | |
| SCHEMBL29067231 | 0.94 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2NPC1L1 | |
| SCHEMBL14107828 | 0.94 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2NPC1L1 | |
| SCHEMBL26324654 | 0.94 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2NPC1L1 | |
| SCHEMBL14371762 | 0.94 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2NPC1L1 | |
| SCHEMBL9010519 | 0.84 | CDC25A (0.76) | CDC25ACDC25BOSBPOSBP2NPC1L1 | |
| SCHEMBL13392701 | 0.82 | CDC25A (0.56) | CDC25ACDC25BOSBPOSBP2NPC1L1 | |
| SCHEMBL3221542 | 0.82 | CDC25A (0.56) | CDC25ACDC25BOSBPOSBP2NPC1L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771789-B1 | 1 alpha, 26-dihydroxy-D-homo-vitamin D3 | HOFFMANN LA ROCHE (CH) | 2000-02-16 | — | — | EP | disclosed |
| EP-0771789-A1 | 1 alpha, 26-dihydroxy-D-homo-vitamin D3 | F. HOFFMANN-LA ROCHE AG (CH) | 1997-05-07 | — | — | EP | disclosed |