SCHEMBL8101065

CC(=O)O[C@H]1CC[C@](C)(C2CC[C@]3(C)[C@@H]([C@H](C)CCCC(C)C)CC[C@H]3C2CC(=O)O)C(=O)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	CDC25A	P30304	12/20	1.00

▸	CDC25B	P30305	1/20	0.72

▸	FNTA	P49354	5/20	0.53

▸	FNTB	P49356	5/20	0.53

▸	CDC45	O75419	2/20	0.53

▸	PTPRC	P08575	1/20	0.53

▸	POLA1	P09884	2/20	0.51

▸	CDC25C	P30307	1/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31612292	0.88	CDC25A (0.79)	CDC25ACDC25BFNTAFNTBCDC45
SCHEMBL13521609	0.86	CDC25A (0.76)	CDC25ACDC25BFNTAFNTBCDC45
7-Oxocholesteryl Acetate SCHEMBL19858751	0.77	NR1H3 (0.77)	CDC25ACDC25BFNTAFNTBPOLA1
7-Oxocholesteryl Acetate SCHEMBL21000253	0.77	NR1H3 (0.77)	CDC25ACDC25BFNTAFNTBPOLA1
7-Oxocholesteryl Acetate SCHEMBL4275934	0.77	NR1H3 (0.77)	CDC25ACDC25BFNTAFNTBPOLA1
7-Oxocholesteryl Acetate SCHEMBL24425752	0.77	NR1H3 (0.77)	CDC25ACDC25BFNTAFNTBPOLA1
7-Oxocholesteryl Acetate SCHEMBL19545214	0.77	NR1H3 (0.77)	CDC25ACDC25BFNTAFNTBPOLA1
7-Oxocholesteryl Acetate SCHEMBL19866270	0.77	NR1H3 (0.77)	CDC25ACDC25BFNTAFNTBPOLA1
7-Oxocholesteryl Acetate SCHEMBL4275938	0.77	NR1H3 (0.77)	CDC25ACDC25BFNTAFNTBPOLA1
7-Oxocholesteryl Acetate SCHEMBL14599124	0.77	NR1H3 (0.77)	CDC25ACDC25BFNTAFNTBPOLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6011058-A	CDC25 PHOSPHATASE INHIBITION PROPERTIES AND ANTI-CANCER ACTIVITY.	GEORGIA TECH RESEARCH CORPORATION (US)	2000-01-04	—	—	US	disclosed