Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087311 | 1.00 | KCNH2 (0.50) | KCNH2SIGMAR1CSNK1ECETPHTR2A | |
| SCHEMBL8098880 | 1.00 | KCNH2 (0.50) | KCNH2SIGMAR1CSNK1ECETPHTR2A | |
| SCHEMBL8087747 | 1.00 | KCNH2 (0.50) | KCNH2SIGMAR1CSNK1ECETPHTR2A | |
| SCHEMBL8094324 | 1.00 | KCNH2 (0.50) | KCNH2SIGMAR1CSNK1ECETPHTR2A | |
| SCHEMBL8086378 | 1.00 | KCNH2 (0.50) | KCNH2SIGMAR1CSNK1ECETPHTR2A | |
| SCHEMBL28615324 | 1.00 | KCNH2 (0.50) | KCNH2SIGMAR1CSNK1ECETPHTR2A | |
| SCHEMBL8094273 | 1.00 | KCNH2 (0.50) | KCNH2SIGMAR1CSNK1ECETPHTR2A | |
| SCHEMBL8095818 | 0.98 | SIGMAR1 (0.52) | KCNH2SIGMAR1CSNK1ECETPHTR2A | |
| SCHEMBL8101237 | 0.92 | SIGMAR1 (0.48) | KCNH2SIGMAR1CNR2 | |
| SCHEMBL28322341 | 0.92 | SIGMAR1 (0.48) | KCNH2SIGMAR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |