Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639246 | 0.93 | F2 (0.67) | F2SMN1; SMN2TP53FNTAFNTB | |
| SCHEMBL8031785 | 0.91 | F2 (0.66) | F2SMN1; SMN2TP53FNTAFNTB | |
| SCHEMBL6634143 | 0.91 | F2 (0.56) | F2SMN1; SMN2TP53FNTAFNTB | |
| SCHEMBL6635152 | 0.91 | F2 (0.66) | F2SMN1; SMN2TP53FNTAFNTB | |
| SCHEMBL6636130 | 0.90 | F2 (0.68) | F2SMN1; SMN2FNTAFNTBPGGT1B | |
| SCHEMBL6634668 | 0.89 | F2 (0.87) | F2SMN1; SMN2TP53HDAC6 | |
| SCHEMBL6634298 | 0.87 | F2 (0.61) | F2SMN1; SMN2FNTAFNTBPGGT1B | |
| SCHEMBL6636057 | 0.86 | F2 (0.57) | F2SMN1; SMN2FNTAFNTBPGGT1B | |
| SCHEMBL6636359 | 0.85 | F2 (0.53) | F2SMN1; SMN2TP53FNTAFNTB | |
| SCHEMBL7430469 | 0.85 | F2 (0.54) | F2SMN1; SMN2TP53FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121308-A | INDOLE AND BENZIMIDAZOLE ANTITHROMBOTIC COMPOUNDS, SUCH AS 1-METHYL-2-(N-(4-AMIDINOPHENYL)-AMINOMETHYL)-5-(N-(HYDROXYCARBONYLMETHYL) -QUINOLINE-8-SULPHONYLAMINO)-INDOLE | BOEHRINGER INGELHEIM KG (DE) | 2000-09-19 | — | — | US | disclosed |