Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.82 |
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.43 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87612 | 0.91 | GBA1 (1.00) | GBA1CCR3SLC6A4CARM1PRMT6 | |
| Bromide SCHEMBL10728442 | 0.89 | GBA1 (0.96) | GBA1CCR3SLC6A4CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL4935892 | 0.89 | GBA1 (0.96) | GBA1CCR3SLC6A4CARM1PRMT6 | |
| SCHEMBL3765342 | 0.87 | GBA1 (0.72) | GBA1CCR3SLC6A4CARM1PRMT6 | |
| Ethylamine SCHEMBL3323945 | 0.86 | GBA1 (0.82) | GBA1CCR3SLC6A4CARM1PRMT6 | |
| Formaldehyde SCHEMBL28466516 | 0.85 | GBA1 (0.89) | GBA1CCR3SLC6A4CARM1PRMT6 | |
| SCHEMBL8891663 | 0.84 | GBA1 (0.85) | GBA1CCR3SLC6A4POLB | |
| SCHEMBL1428015 | 0.84 | GBA1 (0.85) | GBA1CCR3SLC6A4 | |
| SCHEMBL20858759 | 0.83 | GBA1 (0.66) | GBA1CCR3SLC6A4POLB | |
| SCHEMBL595263 | 0.83 | GBA1 (0.59) | GBA1CCR3ALDH1A1ACHECARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998008839-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |