SCHEMBL810176

SCHEMBL810176

C=Cc1ccc(Cl)cc1CCl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.38
CYP3A4 P08684 4/20 0.38
HIF1A Q16665 3/20 0.38
KMT2A Q03164 3/20 0.38
IDO1 P14902 3/20 0.38
MEN1 O00255 2/20 0.38
ALOX15 P16050 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
SLC22A1 O15245 1/20 0.38
USP2 O75604 1/20 0.38
LMNA P02545 1/20 0.38
HSP90AA1 P07900 1/20 0.38
MAPT P10636 1/20 0.38
HSPD1 P10809 1/20 0.38
HSPA5 P11021 1/20 0.38
ALOX12 P18054 1/20 0.38
CASP1 P29466 1/20 0.38
HTT P42858 1/20 0.38
BLM P54132 1/20 0.38
HSPE1 P61604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8170934 0.82 TDP1 (0.41) HPGDCYP3A4HIF1AKMT2AIDO1
SCHEMBL29135543 0.82 PTGDR (0.47) HPGDCYP3A4HIF1AKMT2AIDO1
SCHEMBL15524757 0.82 HPGD (0.36) HPGDCYP3A4HIF1AKMT2AIDO1
SCHEMBL809722 0.81 PTGDR (0.35) HPGDCYP3A4HIF1AKMT2AIDO1
SCHEMBL808751 0.80 ALDH1A1 (0.33) HPGDCYP3A4IDO1TDP1ALDH1A1
SCHEMBL15653272 0.79 TDP1 (0.57) HPGDCYP3A4HIF1AKMT2AIDO1
SCHEMBL30595108 0.79 ALDH1A1 (0.31) ALDH1A1
SCHEMBL1264548 0.79 ALDH1A1 (0.31) ALDH1A1
SCHEMBL810252 0.78 NPSR1 (0.43) HPGDKMT2ATDP1LMNAMAPT
SCHEMBL21838260 0.78 TTR (0.41) HPGDALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9079989-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-07-14 US disclosed
US-20150025213-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-01-22 US disclosed
US-8883946-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-11-11 US disclosed
US-20140080989-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-03-20 US disclosed
WO-2012015977-A3 HIGHLY PORTABLE AND STABLE WORK STATION HERSCHLER MATTHEW B (US) 2012-05-10 WO disclosed
EP-2192645-B1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME TOKUYAMA CORP (JP) 2011-11-30 EP disclosed
US-20110250525-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME TOKUYAMA CORPORATION (JP) 2011-10-13 US disclosed
EP-2192645-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME Tokuyama Corporation (JP) 2010-06-02 EP disclosed