Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095900 | 1.00 | OPRM1 (0.40) | OPRM1KCNH2GRIN2DGRIN3BCHRM2 | |
| SCHEMBL8101337 | 1.00 | OPRM1 (0.40) | OPRM1KCNH2GRIN2DGRIN3BCHRM2 | |
| SCHEMBL8098557 | 1.00 | OPRM1 (0.40) | OPRM1KCNH2GRIN2DGRIN3BCHRM2 | |
| SCHEMBL8086846 | 1.00 | OPRM1 (0.40) | OPRM1KCNH2GRIN2DGRIN3BCHRM2 | |
| SCHEMBL8087483 | 1.00 | OPRM1 (0.40) | OPRM1KCNH2GRIN2DGRIN3BCHRM2 | |
| SCHEMBL8100835 | 1.00 | OPRM1 (0.40) | OPRM1KCNH2GRIN2DGRIN3BCHRM2 | |
| SCHEMBL8100549 | 0.98 | OPRM1 (0.41) | OPRM1KCNH2GRIN2DGRIN3BCHRM2 | |
| SCHEMBL8094488 | 0.93 | CYP1A2 (0.42) | OPRM1KCNH2GRIN2DGRIN3BCHRM2 | |
| SCHEMBL8094316 | 0.86 | OPRM1 (0.44) | OPRM1KCNH2GRIN2DGRIN3BCHRM2 | |
| SCHEMBL28004399 | 0.85 | HTR2A (0.37) | OPRM1KCNH2GRIN2DGRIN3BCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |