Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 14/20 | 0.72 |
| ▸ | RARG | P13631 | 14/20 | 0.72 |
| ▸ | RARA | P10276 | 13/20 | 0.72 |
| ▸ | RXRA | P19793 | 8/20 | 0.68 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | RXRB | P28702 | 5/20 | 0.51 |
| ▸ | RXRG | P48443 | 3/20 | 0.51 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.51 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565430 | 0.91 | RARB (0.70) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL27324962 | 0.88 | RARB (0.66) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9143255 | 0.88 | RARB (0.57) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL3456673 | 0.88 | RARB (0.64) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL10284325 | 0.86 | RARB (0.60) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9186793 | 0.86 | RARB (0.63) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9265392 | 0.85 | RXRA (0.69) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL10976941 | 0.85 | RARB (0.76) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL8461871 | 0.85 | RARB (0.62) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL10976930 | 0.85 | RARB (0.76) | RARBRARGRARARXRACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1285830-A | Pyridylpyrrole derivatives | SANKYO CO (JP) | 2001-02-28 | — | — | CN | disclosed |
| EP-1031572-A1 | PYRIDYLPYRROLE DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-30 | — | — | EP | disclosed |
| EP-0405028-B1 | Thiochroman esters of phenols and terephthalates having retinoid-like activity | ALLERGAN INC (US) | 1995-10-11 | — | — | EP | disclosed |
| US-5015658-A | Treatment of skin disorders such as psoriasis | ALLERGAN, INC. (US) | 1991-05-14 | — | — | US | disclosed |
| EP-0405028-A1 | Thiochroman esters of phenols and terephthalates having retinoid-like activity | ALLERGAN, INC (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4895868-A | PSORIASIS, SKIN DISORDERS, ANTIARTHRITIC, WOUND HEALING, EYE DRYNESS | ALLERGAN, INC. (US) | 1990-01-23 | — | — | US | disclosed |