Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.53 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15542258 | 0.78 | KDM1A (0.55) | KDM1ASLC9A1MAPK1CYP2C19 | |
| SCHEMBL6623618 | 0.78 | KDM1A (0.55) | KDM1ASLC9A1MAPK1CYP2C19 | |
| SCHEMBL28829972 | 0.78 | KDM1A (0.60) | KDM1ARCOR1SLC9A1KDM4EGAA | |
| SCHEMBL15541944 | 0.78 | KDM1A (0.55) | KDM1ASLC9A1MAPK1CYP2C19 | |
| SCHEMBL28885396 | 0.75 | KDM1A (0.51) | KDM1ARCOR1SLC9A1ALDH1A1KDM4E | |
| SCHEMBL15766833 | 0.71 | KDM1A (0.97) | KDM1ARCOR1HTR2CHTR2AHTR2B | |
| SCHEMBL30997748 | 0.71 | SLC9A1 (0.73) | SLC9A1PARP1ALDH1A1KDM4EGLA | |
| SCHEMBL15766835 | 0.71 | KDM1A (0.97) | KDM1ARCOR1HTR2CHTR2AHTR2B | |
| SCHEMBL15780125 | 0.71 | KDM1A (0.97) | KDM1ARCOR1HTR2CHTR2AHTR2B | |
| SCHEMBL2227972 | 0.70 | KDM1A (0.36) | KDM1AALDH1A1DDB1CRBNMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747346-B1 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL MYERS SQUIBB CO (US) | 2000-02-16 | — | — | EP | disclosed |
| EP-0747346-A2 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |