Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 18/20 | 0.41 |
| ▸ | F2 | P00734 | 11/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL860456 | 0.83 | F7 (0.41) | F7F2F10ITGB3ITGA2B | |
| SCHEMBL861396 | 0.77 | F10 (0.39) | F7F2F10ITGB3ITGA2B | |
| SCHEMBL860992 | 0.75 | F7 (0.43) | F7F2F10 | |
| SCHEMBL8102477 | 0.74 | ITGB3 (0.42) | F7F2F10ITGB3ITGA2B | |
| SCHEMBL860491 | 0.74 | F7 (0.46) | F7F2F10ITGB3ITGA2B | |
| SCHEMBL860983 | 0.72 | F7 (0.39) | F7F2F10ITGB3ITGA2B | |
| SCHEMBL860708 | 0.71 | F7 (0.50) | F7F2F10 | |
| SCHEMBL14647037 | 0.70 | F7 (0.51) | F7F2F10 | |
| SCHEMBL860995 | 0.70 | F7 (0.52) | F7F2F10 | |
| SCHEMBL860524 | 0.69 | F7 (0.40) | F7F2F10ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007015-A1 | MALONAMIDE DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY | SANOFI-AVENTIS (FR) | 2009-01-15 | — | — | WO | disclosed |