Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979499 | 0.88 | KMT2A (0.45) | KMT2ASMN1; SMN2PIK3CDBRD4BRD2 | |
| SCHEMBL4211644 | 0.81 | SMN1; SMN2 (0.45) | KMT2ASMN1; SMN2PIK3CDALDH1A1MAPT | |
| SCHEMBL2800309 | 0.80 | SMN1; SMN2 (0.46) | KMT2ASMN1; SMN2PIK3CDBRD4BRD2 | |
| SCHEMBL4199150 | 0.77 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL4200346 | 0.76 | SMN1; SMN2 (0.41) | KMT2ASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL8088805 | 0.76 | KMT2A (0.47) | KMT2ASMN1; SMN2PIK3CDBRD4BRD2 | |
| SCHEMBL8377647 | 0.76 | PIK3CD (0.36) | KMT2ASMN1; SMN2PIK3CDBRD4BRD2 | |
| SCHEMBL9117135 | 0.75 | SMN1; SMN2 (0.45) | KMT2ASMN1; SMN2PIK3CDBRD4BRD2 | |
| SCHEMBL4199141 | 0.75 | SMN1; SMN2 (0.43) | KMT2ASMN1; SMN2PIK3CDALDH1A1MAPT | |
| SCHEMBL2798086 | 0.74 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885933-B1 | One-component alkoxy containing RTV-silicone rubber compositions | WACKER CHEMIE GMBH (DE) | 2000-08-30 | — | — | EP | disclosed |
| US-6018011-A | OBTAINED BY REACTING A POLYORGANOSILOXANE, WITH A REACTION PRODUCT OF AN ORGANOSILANE OF GIVEN FORMULA AND N-1-((METHYLDIETHOXYSILOXY)DIETHOXYSILYL)ETHYL-2-PYRROLIDONE; USE IN ALKOXY-CROSSLINKING RTV SILICONE RUBBER MIXTURES | HUELS SILICONE GMBH (DE) | 2000-01-25 | — | — | US | disclosed |
| US-6001948-A | BASED ON HYDROXY-TERMINATED POLYDIORGANOSILOXANES CONTAINING A TRIALKOXYSILANE WITH A SUBSTITUTED AMIDOALKYL RADICAL, WHICH CAN BE PREPARED USING CONVENTIONAL MIXING TECHNOLOGIES. | WACKER-CHEMIE GMBH (DE) | 1999-12-14 | — | — | US | disclosed |
| EP-0885931-A2 | One-component alkoxy group containing RTV-systems | Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0885933-A1 | One-component alkoxy containing RTV-silicone rubber compositions | Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0885915-A2 | Polyorganosiloxanes having dialkoxyorganosiloxy groups | Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) | 1998-12-23 | — | — | EP | disclosed |