Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4211644 | 0.92 | SMN1; SMN2 (0.45) | KMT2APIK3CDSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL2800309 | 0.90 | SMN1; SMN2 (0.46) | KMT2APIK3CDBRD4BRD2SMN1; SMN2 | |
| SCHEMBL8102441 | 0.88 | KMT2A (0.40) | KMT2APIK3CDBRD4BRD2SMN1; SMN2 | |
| SCHEMBL4199150 | 0.88 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL4200346 | 0.86 | SMN1; SMN2 (0.41) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL4199141 | 0.86 | SMN1; SMN2 (0.43) | KMT2APIK3CDSMN1; SMN2MEN1ACACB | |
| SCHEMBL2798086 | 0.84 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL8088805 | 0.83 | KMT2A (0.47) | KMT2APIK3CDBRD4BRD2SMN1; SMN2 | |
| SCHEMBL8377647 | 0.83 | PIK3CD (0.36) | KMT2APIK3CDBRD4BRD2SMN1; SMN2 | |
| SCHEMBL9117135 | 0.80 | SMN1; SMN2 (0.45) | KMT2APIK3CDBRD4BRD2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885933-B1 | One-component alkoxy containing RTV-silicone rubber compositions | WACKER CHEMIE GMBH (DE) | 2000-08-30 | — | — | EP | claimed |
| US-6020449-A | Alkoxy-crosslinking RTV1 silicone rubber mixtures | WACKER-CHEMIE GMBH (DE) | 2000-02-01 | — | — | US | claimed |
| US-6001948-A | BASED ON HYDROXY-TERMINATED POLYDIORGANOSILOXANES CONTAINING A TRIALKOXYSILANE WITH A SUBSTITUTED AMIDOALKYL RADICAL, WHICH CAN BE PREPARED USING CONVENTIONAL MIXING TECHNOLOGIES. | WACKER-CHEMIE GMBH (DE) | 1999-12-14 | — | — | US | claimed |
| EP-0885931-A2 | One-component alkoxy group containing RTV-systems | Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) | 1998-12-23 | — | — | EP | claimed |
| EP-0885933-A1 | One-component alkoxy containing RTV-silicone rubber compositions | Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) | 1998-12-23 | — | — | EP | claimed |
| EP-0885915-A2 | Polyorganosiloxanes having dialkoxyorganosiloxy groups | Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) | 1998-12-23 | — | — | EP | claimed |
| US-20180201634-A1 | DEHYDROGENATIVE SILYLATION, HYDROSILYLATION AND CROSSLINKING USING PYRIDINEDIIMINE COBALT CARBOXYLATE CATALYSTS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2018-07-19 | — | — | US | disclosed |
| US-20090191375-A1 | ADHESIVE JOINT SEALED WITH SILICONE | SIKA TECHNOLOGY AG (CH) | 2009-07-30 | — | — | US | disclosed |
| EP-2057341-A1 | ADHESIVE JOINT SEALED WITH SILICONE | Sika Technology AG (CH) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008000833-A1 | ADHESIVE JOINT SEALED WITH SILICONE | SIKA TECHNOLOGY AG (CH) | 2008-01-03 | — | — | WO | disclosed |
| EP-1873344-A1 | Silicone sealed bonding | Sika Technology AG (CH) | 2008-01-02 | — | — | EP | disclosed |
| EP-0885933-B1 | One-component alkoxy containing RTV-silicone rubber compositions | WACKER CHEMIE GMBH (DE) | 2000-08-30 | — | — | EP | disclosed |
| US-6020449-A | Alkoxy-crosslinking RTV1 silicone rubber mixtures | WACKER-CHEMIE GMBH (DE) | 2000-02-01 | — | — | US | disclosed |
| US-6018011-A | OBTAINED BY REACTING A POLYORGANOSILOXANE, WITH A REACTION PRODUCT OF AN ORGANOSILANE OF GIVEN FORMULA AND N-1-((METHYLDIETHOXYSILOXY)DIETHOXYSILYL)ETHYL-2-PYRROLIDONE; USE IN ALKOXY-CROSSLINKING RTV SILICONE RUBBER MIXTURES | HUELS SILICONE GMBH (DE) | 2000-01-25 | — | — | US | disclosed |
| US-6001948-A | BASED ON HYDROXY-TERMINATED POLYDIORGANOSILOXANES CONTAINING A TRIALKOXYSILANE WITH A SUBSTITUTED AMIDOALKYL RADICAL, WHICH CAN BE PREPARED USING CONVENTIONAL MIXING TECHNOLOGIES. | WACKER-CHEMIE GMBH (DE) | 1999-12-14 | — | — | US | disclosed |
| EP-0885931-A2 | One-component alkoxy group containing RTV-systems | Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0885915-A2 | Polyorganosiloxanes having dialkoxyorganosiloxy groups | Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0885933-A1 | One-component alkoxy containing RTV-silicone rubber compositions | Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) | 1998-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180201634-A1 | DEHYDROGENATIVE SILYLATION, HYDROSILYLATION AND CROSSLINKING USING PYRIDINEDIIMINE COBALT CARBOXYLATE CATALYSTS | YAP1, CTCF, SIRT3 | KMT2A 868/4885PIK3CD 4114/4885BRD4 474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.