Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 17/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5629970 | 0.79 | OPRK1 (0.78) | OPRK1OPRD1OPRM1CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL7978518 | 0.71 | OPRK1 (0.40) | OPRK1OPRD1OPRM1CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL7978516 | 0.71 | OPRK1 (0.40) | OPRK1OPRD1OPRM1CYP2D6CYP3A4 | |
| SCHEMBL6478912 | 0.69 | OPRK1 (0.64) | OPRK1OPRD1OPRM1CYP2D6CYP3A4 | |
| SCHEMBL8102521 | 0.68 | OPRK1 (0.35) | OPRK1OPRD1OPRM1CYP2D6CYP3A4 | |
| SCHEMBL5631920 | 0.64 | OPRK1 (0.77) | OPRK1OPRD1OPRM1CYP2D6CYP3A4 | |
| SCHEMBL20832991 | 0.64 | CYP2D6 (0.56) | CYP2D6TSHR | |
| SCHEMBL20833013 | 0.64 | CYP2D6 (0.56) | CYP2D6TSHR | |
| SCHEMBL22259900 | 0.64 | CYP2D6 (0.56) | CYP2D6TSHR | |
| SCHEMBL8507267 | 0.64 | CYP2D6 (0.56) | CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028063-A | ADMINISTERING COMPOUND WITH OPIOID ACTIVITY | ADOLOR CORPORATION (US) | 2000-02-22 | — | — | US | claimed |