Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 10/20 | 0.49 |
| ▸ | RARB | P10826 | 9/20 | 0.49 |
| ▸ | RARA | P10276 | 9/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | BLVRB | P30043 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8839114 | 0.88 | RARG (0.57) | RARGRARBRARACYP26A1KMT2A | |
| SCHEMBL8093046 | 0.84 | RARB (0.64) | RARGRARBRARACYP26A1KMT2A | |
| SCHEMBL8103042 | 0.82 | RARB (0.47) | RARGRARBRARACYP26A1KMT2A | |
| SCHEMBL8758241 | 0.81 | RARB (0.46) | RARGRARBRARACYP26A1KMT2A | |
| SCHEMBL8093109 | 0.80 | RARG (0.43) | RARGRARBRARACYP26A1KMT2A | |
| SCHEMBL8556007 | 0.80 | RARB (0.50) | RARGRARBRARACYP26A1KMT2A | |
| SCHEMBL8102916 | 0.80 | RARB (0.51) | RARGRARBRARACYP26A1KMT2A | |
| SCHEMBL7511656 | 0.78 | RARA (0.77) | RARGRARBRARACYP26A1KMT2A | |
| SCHEMBL8906913 | 0.78 | CYP26A1 (0.50) | RARGRARBRARACYP26A1KMT2A | |
| SCHEMBL8106316 | 0.78 | CYP26A1 (0.44) | RARGRARBRARACYP26A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709867-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-20 | — | — | US | claimed |
| EP-0661260-B1 | New bi-aromatic compounds derived from amides pharmaceutical compositions and cosmetic compositions containing them and their use | CIRD GALDERMA (FR) | 1997-03-12 | — | — | EP | claimed |
| US-6051243-A | USEFUL IN THE TOPICAL AND SYSTEMIC TREATMENT OF DERMATOLOGICAL CONDITIONS ASSOCIATED WITH A KERATINIZATION DISORDER, DERMATOLOGICAL CONDITIONS (AND THE LIKE) INCLUDING AN INFLAMMATORY AND/OR IMMUNOALLERGIC COMPONENT | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2000-04-18 | — | — | US | disclosed |
| US-5709867-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-20 | — | — | US | disclosed |