Tetrahydrofuran

Tetrahydrofuran

SCHEMBL8102693

C1=CCC([Ti+2]C2=CC=CC2)=C1.C1CCOC1.[Cl-].[Cl-].[Cl-].[Li+]

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Tetrahydrofuran. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL184055 0.84
Hydrochloric Acid SCHEMBL16583677 0.82
Hydrochloric Acid SCHEMBL3671246 0.82
Lithium Ion SCHEMBL11293697 0.82
Bromide SCHEMBL2933690 0.82
SCHEMBL4576019 0.79
SCHEMBL1450260 0.79
Bromide SCHEMBL863760 0.79
Iodide SCHEMBL1674727 0.79
SCHEMBL2809938 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6057467-A CYCLOPENTADIENE LIGANDS WITH GROUP IVB METALS RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPEC (CN) 2000-05-02 US disclosed