Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.74 |
| ▸ | AR | P10275 | 1/20 | 0.74 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 4/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102696 | 1.00 | MAOB (0.74) | MAOBARABCG2MAPTACHE | |
| SCHEMBL29211623 | 0.90 | ABCG2 (0.66) | MAOBARABCG2MAPTACHE | |
| SCHEMBL5084274 | 0.85 | AR (1.00) | MAOBARABCG2MAPTACHE | |
| SCHEMBL5084268 | 0.85 | AR (1.00) | MAOBARABCG2MAPTACHE | |
| SCHEMBL30807180 | 0.85 | AR (1.00) | MAOBARABCG2MAPTACHE | |
| SCHEMBL5138170 | 0.84 | MAOB (0.82) | MAOBARABCG2MAPTACHE | |
| SCHEMBL5138171 | 0.84 | MAOB (0.82) | MAOBARABCG2MAPTACHE | |
| SCHEMBL7097152 | 0.84 | ABCG2 (0.63) | MAOBARABCG2MAPTACHE | |
| SCHEMBL19880069 | 0.83 | AURKA (0.82) | MAOBARABCG2MAPTNR1H4 | |
| SCHEMBL29270985 | 0.83 | MAPT (0.66) | MAOBARABCG2MAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046231-A | ADMINISTERING A SUFFICIENT AMOUNT OF A CANCER CHEMOPREVENTATIVE COMPOSITION COMPRISING 4'-BROMOFLAVONE TO A MAMMAL IN NEED TO PREVENT, DELAY OR REVERSE A CANCER SENSITIVE TO 4'-BROMOFLAVONE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2000-04-04 | — | — | US | disclosed |